Solmax/Solmax Forte/Solmax Kids

Solmax/Solmax Forte/Solmax Kids

carbocisteine

Manufacturer:

Great Eastern Drug

Distributor:

Zuellig Pharma
Full Prescribing Info
Contents
Carbocisteine.
Description
Solmax: Each capsule contains Carbocisteine 500 mg.
Solmax Forte: Each 5ml suspension contains Carbocisteine 500 mg.
Solmax Kids: Each 5 ml suspension contains Carbocisteine 200 mg.
Solmax is a normalizer of mucus in the air passages. It is available in pediatric and adult suspension to treat cough characterized by thick and abundant secretions associated with respiratory disorders in children and adults.
Action
Pharmacology: Carbocisteine normalizes the viscosity (thickness) of secretions in the respiratory tract in several possible ways. It may act on the mucus-producing cells, modifying their internal processes so that they secrete mucus that is "thin" and less adhesive. If thick phlegm is already formed, Carbocisteine may act on it by alternating its physicochemical properties. This results in loosening of the mucus fibers of the thick secretion to facilitate its elimination by the cough mechanism.
Pharmacokinetics:
Carbocisteine is rapidly and well absorbed after oral administration. Following oral administration of 1.5g Carbocisteine, peak serum concentrations of 13-16 mg/L were reached in 1-2 hours. Plasma half-life was 1.5 to 2 hours. Carbocisteine penetrates well into lung tissues and respiratory mucus, suggesting local action. Carbocisteine undergoes acetylation, decarboxylation, and sulfoxidation. Majority of the drug is excreted unchanged in the urine.
Indications/Uses
Mucolytic agent for relief of cough associated with acute and chronic bronchitis, asthma, bronchiectasis and emphysema.
Dosage/Direction for Use
Solmax Capsule: Adult and children >12 yr 1 capsule 3 times a day after meal.
Solmax Forte: Children 5-12 years: 2.5 ml or ½ teaspoon 3-4 times per day or 5 ml 2 times per day.
Adult: 5 ml or 1 teaspoonful 3 times a day.
Solmax Kids: Children 2-5 years: 2.5 ml or ½ teaspoon 3-4 times per day or 5 ml 2 times per day.
5-12 years: 5 ml or 1 teaspoonful 3 times per day.
Mode of Administration: For oral administration.
Overdosage
Acute overdose; gastrointestinal disturbance is the only likely symptom and no active treatment is necessary.
Contraindications
Contraindicated in patients with active peptic ulcer or with known hypersensitivity to Carbocisteine.
Warnings
Administer with caution in patients with history of gastric or duodenal ulcer.
Administer to infants only as advised by the physician.
Use in Pregnancy: Do not recommend the use of Carbocisteine in the first-trimester of pregnant.
Special Precautions
Administer with caution in patients with history of gastric or duodenal ulcer. Since the effects of Carbocisteine when used during pregnancy or lactation are not known, it should be administered with caution to women during these periods. Administer to infants only as advised by the physician.
Use In Pregnancy & Lactation
Solmax Kids: Use in Pregnancy: While there are no reports of teratogenic effects, the manufacturers do not recommend the use of Carbocisteine in the first trimester.
Use in Lactation: No information available.
Adverse Reactions
Nausea, headache, diarrhea, gastric discomfort, gastrointestinal bleeding, and skin rash have occasionally occurred.
Drug Interactions
Concomitant administration with Carbocisteine enhances the absorption of sodium amoxicillin.
Pretreatment with cimetidine severely impairs the urinary elimination of Carbocisteine sulfoxides.
Storage
Store at temperature not exceeding 30°C.
MIMS Class
Cough & Cold Preparations
ATC Classification
R05CB03 - carbocisteine ; Belongs to the class of mucolytics. Used in the treatment of wet cough.
Presentation/Packing
Form
Solmax cap 500 mg
Packing/Price
10 × 25's
Form
Solmax Forte oral susp 500 mg/5 mL
Packing/Price
1's
Form
Solmax Kids susp 200 mg/5 mL
Packing/Price
60 mL x 1's
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